LEAP2

LEAP2 is an endogenous peptide that functions as the first known natural antagonist of the ghrelin receptor. Researchers study its role in appetite regulation and metabolism.

In the literature, LEAP2 appears most often in work focused on appetite control and metabolism. Studies in this area tend to look at mechanisms and observed effects in laboratory and preclinical settings rather than outcomes in people, so the picture is best read as a map of where researchers have been curious — not as evidence of any benefit.

LEAP2 is catalogued here under powder peptides. Coverage of this compound varies in quality and depth, and much of it remains early-stage. Reading the underlying research directly is the only way to judge how strong any particular finding is.